FlexVarJM - Estimate Joint Models with Subject-Specific Variance

Estimation of mixed models including a subject-specific variance which can be time and covariate dependent. In the joint model framework, the package handles left truncation and allows a flexible dependence structure between the competing events and the longitudinal marker. The estimation is performed under the frequentist framework, using the Marquardt-Levenberg algorithm. (Courcoul, Tzourio, Woodward, Barbieri, Jacqmin-Gadda (2023) <arXiv:2306.16785>).